Lamina cribrosa pore movement during acute intraocular pressure rise
نویسندگان
چکیده
منابع مشابه
Application of Elliptic Fourier analysis to describe the lamina cribrosa shape with age and intraocular pressure.
The lamina cribrosa (LC) plays an important biomechanical role in the optic nerve head (ONH). We developed a statistical shape model of the LC and tested if the shape varies with age or IOP. The ONHs of 18 donor eyes (47-91 years, mean 76 years) fixed at either 5 or 50 mmHg of IOP were sectioned, stained, and imaged under a microscope. A 3D model of each ONH was reconstructed and the outline of...
متن کاملIn Vivo Three-Dimensional Lamina Cribrosa Strains in Healthy, Ocular Hypertensive, and Glaucoma Eyes Following Acute Intraocular Pressure Elevation.
Purpose To compare in vivo lamina cribrosa (LC) strains (deformations) following acute IOP elevation in healthy, glaucoma, and ocular hypertensive subjects. Methods There were 20 healthy, 20 high-tension primary open-angle glaucoma (POAG), 16 primary angle-closure glaucoma (PACG), and 20 ocular hypertensive (OHT; with normal visual fields) eyes studied. For each test eye, the optic nerve head...
متن کاملIncreased elastin expression in astrocytes of the lamina cribrosa in response to elevated intraocular pressure.
PURPOSE To determine whether abnormal elastin synthesis in the glaucomatous optic nerve head and lamina cribrosa is due to elevated intraocular pressure (IOP) or secondary to axonal injury, monkeys with elevated IOP and with optic nerve transection were compared. METHODS Unilateral, chronic elevated IOP was induced in 11 rhesus monkeys by laser scarification of the trabecular meshwork. IOP wa...
متن کاملRelationship between corneal hysteresis and lamina cribrosa displacement after medical reduction of intraocular pressure
PURPOSE To evaluate the relationship between the displacement of the lamina cribrosa (LC) and prelaminar tissue with corneal hysteresis (CH) using spectral-domain coherence tomography (SD-OCT) after reducing intraocular pressure (IOP) with medical treatment. METHODS Sixty-one eyes of 61 patients with ocular hypertension or primary open-angle glaucoma who were going to start with treatment wer...
متن کاملDisplacement of the Lamina Cribrosa in Response to Acute Intraocular Pressure Elevation in Normal Individuals of African and European Descent
PURPOSE To assess if the in vivo mechanical displacement of the anterior laminar cribrosa surface (ALCS) as a response of an acute elevation in intraocular pressure (IOP) differs in individuals of European (ED) and African descent (AD). METHODS Spectral-domain optical coherence tomography (SDOCT) scans were obtained from 24 eyes of 12 individuals of AD and 18 eyes of 9 individuals of ED at th...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 2019
ISSN: 0007-1161,1468-2079
DOI: 10.1136/bjophthalmol-2019-314016